6 Water Purification Methods For Cleanrooms

6 Water Purification Methods For Cleanrooms Medium Image

Water. It makes up 70% of our bodies, but, even more importantly, it serves as a vital ingredient and manufacturing component in cleanrooms. Before we are able to introduce it into the cleanroom setting - especially as part of the product, such as in injectables and other pharmaceuticals - it needs to be purified. We’ve outlined six of the most popular and effective water purification methods used in cleanrooms.

Microporous Filters

A microporous filter is exactly what it sounds like: a filter containing pores of different sizes depending on your requirements. Water is passed through the filter, and large particles are sloughed off.

While this method in and of itself is not sufficient to create clean enough water for injectables, it is considered a vital part of any clean water purification system.

during ultrafiltration all particles and pathogenic microorganisms are retained on a porous membrane while water and dissolved salts pass through Source: EAWAG (n.y.).


Reverse Osmosis (RO)

Reverse Osmosis is a powerful water purification method that typically eliminates around 90% to 99% of ionic contamination. It also removes most organic contamination from the water. It does have a drawback, though, as it does not remove non-ionic particles weighing <100 Dalton as well as it sifts out larger particles. It also does not remove dissolved gases. But since it is able to remove so many contaminants, it is considered one of the most cost-effective options. To remove even more contaminants, it is often paired with ion exchange or electro-deionization.


So how exactly does RO work?