{"id":10239,"date":"2023-01-04T05:42:00","date_gmt":"2023-01-04T05:42:00","guid":{"rendered":"https:\/\/www.golighthouse.com\/en\/?post_type=knowledge-center&#038;p=10239"},"modified":"2022-12-21T18:24:12","modified_gmt":"2022-12-21T18:24:12","slug":"compounding-pharmacist-need-to-know","status":"publish","type":"knowledge-center","link":"https:\/\/www.golighthouse.com\/en\/blog\/compounding-pharmacist-need-to-know\/","title":{"rendered":"10 Things Every Compounding Pharmacist Should Know"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"10239\" class=\"elementor elementor-10239\" data-elementor-post-type=\"knowledge-center\">\n\t\t\t\t\t\t<section data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-section elementor-top-section elementor-element elementor-element-ad8cc06 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ad8cc06\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-91d72c1\" data-id=\"91d72c1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4b7d1ca elementor-widget elementor-widget-text-editor\" data-id=\"4b7d1ca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Whether you are a new compounding pharmacist or have been around for a while, you know that compound pharmacies are unique. In your workspace, you have to gown and operate under strict contamination control protocols, but do you know why?<\/span><\/p><p><span style=\"font-weight: 400;\">As the world\u2019s clean air experts, we\u2019re here to help explain exactly what\u2019s going on and why it matters!<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-59d1b38 elementor-widget elementor-widget-heading\" data-id=\"59d1b38\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">You Work In A Cleanroom!\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-41905c5 elementor-widget elementor-widget-text-editor\" data-id=\"41905c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">When you imagine a cleanroom, what comes to mind? A sterile white room, filled with delicate equipment and workers gowned from head to toe? That situation definitely exists, but there are a wide variety of cleanrooms. The <\/span><a href=\"https:\/\/www.iso.org\/home.html\"><span style=\"font-weight: 400;\">International Organization for Standardization (ISO)<\/span><\/a><span style=\"font-weight: 400;\"> has a number of classifications for cleanrooms. These <\/span><a href=\"https:\/\/www.golighthouse.com\/en\/blog\/cleanroom-classifications-explained-486\/\"><span style=\"font-weight: 400;\">classifications<\/span><\/a><span style=\"font-weight: 400;\"> range from ISO 1 to ISO 9, where ISO 1 is the cleanest and ISO 9 is normal room air. The classifications are defined by how many particles and their size are found in a square meter of air through regular testing. Typically in a pharmacy, classification is performed every 6 months, but routine monitoring should be conducted daily (if not continuously) to ensure classification standards are met.\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">The <\/span><a href=\"https:\/\/www.pharmacytimes.com\/view\/2006-08-5799\"><span style=\"font-weight: 400;\">United States Pharmacopeia (USP) dictates<\/span><\/a><span style=\"font-weight: 400;\"> that critical areas, or a central location where sterile work occurs, should be maintained at an ISO 5 classification. This means that there should be fewer than 3,520 particles, at 0.5 microns, in each cubic meter of air.\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dc25be7 elementor-widget elementor-widget-heading\" data-id=\"dc25be7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Your Workspace Is Not The Only Space That Matters\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b0e8a55 elementor-widget elementor-widget-text-editor\" data-id=\"b0e8a55\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">While the critical area is where the primary compounding occurs, the supporting areas around the central location are also important. This is where non-sterile components, in-process materials, equipment, containers, and formulated products are handled. These areas should be maintained at an ISO 6 or 7 classification, depending on the area\u2019s applications. Behind the scenes, in the design of your pharmacy, the airflow between these areas also matters! But more on that later.\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f46c30b elementor-widget elementor-widget-heading\" data-id=\"f46c30b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">You Are The Primary Source Of Contamination In Your Pharmacy\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1770013 elementor-widget elementor-widget-text-editor\" data-id=\"1770013\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Consistently, <\/span><a href=\"https:\/\/www.researchgate.net\/publication\/242715716_Aseptic_Processing_A_Review_of_Current_Industry_Practice\"><span style=\"font-weight: 400;\">humans are the main source of contamination<\/span><\/a><span style=\"font-weight: 400;\"> in every form of a cleanroom. If humans are present, so is the risk of contamination. To prevent contaminating your materials, it is critical that you properly gown with approved gowns, gloves, face masks, etc. Regular training can help keep this top of mind.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d3a35f elementor-widget elementor-widget-heading\" data-id=\"3d3a35f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Gowning Is Not Just For Your Safety<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-77136ad elementor-widget elementor-widget-text-editor\" data-id=\"77136ad\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Speaking of gowning, did you know it\u2019s not for your safety? While gowning does protect you, it is primarily for the safety of those who are taking the medication. Thus, sloppy gowning practices don\u2019t put you at risk: they put your patients at risk.\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-efe1917 elementor-widget elementor-widget-heading\" data-id=\"efe1917\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Viable Particles Are Your Unseen Enemy\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eacc3b9 elementor-widget elementor-widget-text-editor\" data-id=\"eacc3b9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">To maintain ISO classifications, routine or continuous monitoring of air particle contamination is required. As clean air experts, we highly recommend continuous monitoring for best results. But this type of monitoring really only looks at nonviable particles. These are particles that are non-living organisms, so knowing their size and number is important, but it\u2019s missing a critical piece of information\u2026<\/span><\/p><p><span style=\"font-weight: 400;\">Will it grow?<\/span><\/p><p><span style=\"font-weight: 400;\">Viable particles are living microorganisms, like yeast, mold, and fungi. This type of contamination presents a unique risk because it can grow and spread at an alarming rate. In a normal particle counter, they just present as a particle. But using an <\/span><a href=\"https:\/\/www.golighthouse.com\/en\/blog\/features-active-air-sampler\/\"><span style=\"font-weight: 400;\">active air sampler<\/span><\/a><span style=\"font-weight: 400;\"> will tell you if the contamination is viable. This type of particle monitoring is more complex, so it is not yet routine practice. It is, though, incredibly valuable.\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-389365b elementor-widget elementor-widget-heading\" data-id=\"389365b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Your Must Classify A Compounding Pharmacy Every 6 Months<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-96bd1c5 elementor-widget elementor-widget-text-editor\" data-id=\"96bd1c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">The USP dictates that a compounding pharmacy must complete classification steps every 6 months to maintain its status.\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c582fea elementor-widget elementor-widget-heading\" data-id=\"c582fea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Temperature Matters<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6d71010 elementor-widget elementor-widget-text-editor\" data-id=\"6d71010\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">In all cleanrooms, temperatures matter, but this is especially true in compounding pharmacies. This is maintained through air flow and carefully filtered HVAC systems. In a compounding pharmacy, your working environment should be between 20 to 25\u00b0C (68 to 77\u00b0F). This helps create stability in materials, as well as comfort for employees.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-931e6ab elementor-widget elementor-widget-heading\" data-id=\"931e6ab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Air Flow Matters\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1220606 elementor-widget elementor-widget-text-editor\" data-id=\"1220606\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Air flow is one of the most important design factors in a cleanroom. Air flowing into a cleanroom needs to pass through a <\/span><a href=\"https:\/\/www.golighthouse.com\/en\/blog\/4-cleanroom-particle-filtration-techniques-591\/\"><span style=\"font-weight: 400;\">variety of filters<\/span><\/a><span style=\"font-weight: 400;\"> and then it should continuously move. Stagnant air can increase contamination risk, whereas moving air can move contamination out of the room. But this does also mean there is the risk of moving contaminants. Thus, the cleanest air should be found in the strictest clean zones and move out towards less strict areas. For example, air should NOT move from an ISO 7 supporting area to an ISO 5 critical area.\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">This is called <\/span><a href=\"https:\/\/www.golighthouse.com\/en\/blog\/your-ultimate-guide-to-cleanroom-air-distribution-strategy-590\/\"><span style=\"font-weight: 400;\">laminar flow<\/span><\/a><span style=\"font-weight: 400;\">! It is the foundation of a cleanroom air distribution strategy.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c0403f5 elementor-widget elementor-widget-heading\" data-id=\"c0403f5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Sensors Are Your Friends\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7b2bcf0 elementor-widget elementor-widget-text-editor\" data-id=\"7b2bcf0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Your environment is critical in a compounding pharmacy, and sensors can keep you on track. These don\u2019t even have to be complex monitors, like particle counters, but can be simple sensors to keep your pharmacy in check. These include air pressure sensors, humidity sensors, and thermometers.\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7b65007 elementor-widget elementor-widget-heading\" data-id=\"7b65007\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">You Need An Contamination Control Plan<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31cceae elementor-widget elementor-widget-text-editor\" data-id=\"31cceae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">In the <\/span><a href=\"https:\/\/www.pppmag.com\/article\/pppv16n4s1\"><span style=\"font-weight: 400;\">2019 USP &lt;797&gt; Compliance Survey<\/span><\/a><span style=\"font-weight: 400;\">, only 66% of respondents reported having a plan to establish formal environmental monitoring. As a reminder: a compounding pharmacy is a form of a cleanroom. The foundation of a cleanroom is being clean and the only way to ensure compliance and true cleanliness is through regular environmental monitoring. A contamination control plan (CCP) is how you make sure this happens. A CCP should include sample locations, collection method, and sample volume based on a critical risk assessment.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-12c8284 elementor-widget elementor-widget-heading\" data-id=\"12c8284\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">How Can You Perfect Your Contamination Control Plan?\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7e59f0b elementor-widget elementor-widget-text-editor\" data-id=\"7e59f0b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">If you\u2019re looking to up your contamination control knowledge and better understand your workplace, we recommend exploring our FREE Knowledge Center! We\u2019ve been the world\u2019s clean air experts for 40+ years and we\u2019ve compiled that knowledge into easy to understand articles, videos, and white papers, which are all available for free through our Knowledge Center.<\/span><\/p><p><a href=\"https:\/\/www.golighthouse.com\/en\/knowledge-center-login\/?return=%2Fen%2Fknowledge-center%2F\"><span style=\"font-weight: 400;\">Create your free account today!<\/span><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"featured_media":10240,"template":"","kc_format":[63],"kc_topics":[70],"class_list":["post-10239","knowledge-center","type-knowledge-center","status-publish","has-post-thumbnail","hentry","kc_format-blog","kc_topics-industry-knowledge"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>10 Things Every Compounding Pharmacist Should Know - LWS Knowledge Center<\/title>\n<meta name=\"description\" content=\"A compounding pharmacy is a cleanroom and should operate as such. 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